Toxic and trace element analysis of surface sediments from the Gulf of Saros by INAA and XRF methods

Some surface sediment samples, collected from 53 sampling sites of the Saros Gulf, were analyzed quantitatively by radioisotope energy dispersive X-ray fluorescence (EDXRF) and instrumental neutron activation analysis (INAA). Results indicated some correlations between Rb and Sr (r = 0.64), Fe2O3 and MnO (r = 0.59), Th and La (r = 0.71), Th and Ce (r = 0.64), Th and Sm (r = 0.60), concentration pairs. U and Th results are found to be compatible with those given in the literature for marine sediments

Causative pathogens and antibiotic resistance in diabetic foot infections: A prospective multi-center study

Gencer, Serap/0000-0002-3217-6305; GENCER, SERAP/0000-0002-3217-6305; Yasar, Kadriye Kart/0000-0003-2963-4894; Bozkurt, Fatma/0000-0002-9807-8257; demirdal, tuna/0000-0002-9046-5666; Uzun, Gunalp/0000-0002-8717-6230; Hosoglu, Salih/0000-0002-4034-9202; ERTURK, AYSE/0000-0001-6413-9165; hatipoglu, mustafa/0000-0001-9910-1650; yanik yalcin, tugba/0000-0001-5996-8639; Uysal, Serhat/0000-0002-4294-5999; altay, fatma aybala/0000-0002-7149-2968; Eren, Esma/0000-0002-2712-9694; Lipsky, Benjamin A./0000-0001-9886-5114WOS: 000378759700027PubMed: 26965794Aim: Clinical practice guidelines for the management of diabetic foot infections developed by the Infectious Diseases Society of America (IDSA) are commonly used worldwide. the issue of whether or not these guidelines need to be adjusted for local circumstances, however, has seldom been assessed in large prospective trials. Methods: the Turk-DAY trial was a prospective, multi-center study in which infectious disease specialists from centers across Turkey were invited to participate (NCT02026830). Results: A total of 35 centers throughout Turkey enrolled patients in the trial. Overall, investigators collected a total of 522 specimens from infected diabetic foot wounds for culture from 447 individual patients. Among all isolates, 36.4% were gram-positive organisms, with Staphylococcus aureus the most common among these (11.4%). Gram-negative organisms constituted 60.2% of all the isolates, and the most commonly isolated gram-negative was Escherichia coli (15%). the sensitivity rates of the isolated species were remarkably low for several antimicrobials used in the mild infection group. Conclusions: Based on our findings, several of the antimicrobials frequently used for empirical treatment, including some also recommended in the IDSA guidelines, would not be optimal for treating diabetic foot infections in Turkey. Although the IDSA guideline recommendations may be helpful to guide empiric antimicrobial therapy of DFIs, they should be adjusted to local conditions. (C) 2016 Elsevier Inc. All rights reserved

Author Correction: A new ape from Türkiye and the radiation of late Miocene hominines (Communications Biology, (2023), 6, 1, (842), 10.1038/s42003-023-05210-5)

Correction to: Communications Biology, published online 23 August 2023. In the original version of the Article, two authors and their affiliations were omitted. In the original version of the Article, author first names were not provided for all authors. The corrected author list and affiliations are provided below. This has now been corrected in the HTML and PDF versions of the article. Ayla Sevim-Erol1, David R. Begun2, Alper Yavuz3, Erhan Tarhan4, Çilem Sönmez Sözer1, Serdar Mayda5, Lars W. van den Hoek Ostende6, Robert M. G. Martin2 ;amp; M. Cihat Alçiçek7 1 Ankara University, Faculty of Languages History and Geography, Department of Anthropology, Ankara, Türkiye 2 Department of Anthropology, University of Toronto, Toronto, ON, Canada 3 Mehmet Akif Ersoy University of Science and Letters, Department of Anthropology, Burdur, Türkiye 4 Hitit University Faculty of Science and Letters, Department of Anthropology, Çorum, Türkiye 5 Ege University Fakulty of Science, Department of Biology, İzmir, Türkiye 6 Naturalis Biodiversity Center, Leiden, The Netherlands 7 Pamukkale University, Department of Geology, 20070 Denizli, Türkiye The Author Contributions section should read “A.S.E. is the PR of the project, secured funding for excavations and lab analysis and directed excavations. A.S.E. and D.R.B. are responsible for data curation, acquired funding and supervised research. D.R.B. conceptualized the analysis, conducted the investigation, developed the methodology, prepared the original draft and all subsequent versions. C.S.S., S.M., L.W.vdH. and C.A. contributed their analysis of geological and paleontological results. R.M.G.M. was responsible for the segmentation and analysis of the scans of the mandible. A.Y and E.T. participated in the excavations.” This has now been corrected in the HTML and PDF versions of the article. © 2023, Springer Nature Limited

Causative pathogens and antibiotic resistance in diabetic foot infections: A prospective multi-center study

WOS: 000378759700027PubMed ID: 26965794Aim: Clinical practice guidelines for the management of diabetic foot infections developed by the Infectious Diseases Society of America (IDSA) are commonly used worldwide. The issue of whether or not these guidelines need to be adjusted for local circumstances, however, has seldom been assessed in large prospective trials. Methods: The Turk-DAY trial was a prospective, multi-center study in which infectious disease specialists from centers across Turkey were invited to participate (NCT02026830). Results: A total of 35 centers throughout Turkey enrolled patients in the trial. Overall, investigators collected a total of 522 specimens from infected diabetic foot wounds for culture from 447 individual patients. Among all isolates, 36.4% were gram-positive organisms, with Staphylococcus aureus the most common among these (11.4%). Gram-negative organisms constituted 60.2% of all the isolates, and the most commonly isolated gram-negative was Escherichia coli (15%). The sensitivity rates of the isolated species were remarkably low for several antimicrobials used in the mild infection group. Conclusions: Based on our findings, several of the antimicrobials frequently used for empirical treatment, including some also recommended in the IDSA guidelines, would not be optimal for treating diabetic foot infections in Turkey. Although the IDSA guideline recommendations may be helpful to guide empiric antimicrobial therapy of DFIs, they should be adjusted to local conditions. (C) 2016 Elsevier Inc. All rights reserved

The genetic history of the Southern Arc: a bridge between West Asia and Europe

By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic period and Bronze Age (about 5000 to 1000 BCE), when extensive gene flow entangled it with the Eurasian steppe. Two streams of migration transmitted Caucasus and Anatolian/Levantine ancestry northward, and the Yamnaya pastoralists, formed on the steppe, then spread southward into the Balkans and across the Caucasus into Armenia, where they left numerous patrilineal descendants. Anatolia was transformed by intra?West Asian gene flow, with negligible impact of the later Yamnaya migrations. This contrasts with all other regions where Indo-European languages were spoken, suggesting that the homeland of the Indo-Anatolian language family was in West Asia, with only secondary dispersals of non-Anatolian Indo-Europeans from the steppe. Stories about the peopling?and people?of Southern Europe and West Asia have been passed down for thousands of years, and these stories have contributed to our historical understanding of populations. Genomic data provide the opportunity to truly understand these patterns independently from written history. In a trio of papers, Lazaridis et al. examined more than 700 ancient genomes from across this region, the Southern Arc, spanning 11,000 years, from the earliest farming cultures to post-Medieval times (see the Perspective by Arbuckle and Schwandt). On the basis of these results, the authors suggest that earlier reliance on modern phenotypes and ancient writings and artistic depictions provided an inaccurate picture of early Indo-Europeans, and they provide a revised history of the complex migrations and population integrations that shaped these cultures. ?SNV A web of migrations between Anatolia, its neighbors, and the Steppe suggests a West Asian origin of Indo-Anatolian languages

Ancient DNA from Mesopotamia suggests distinct Pre-Pottery and Pottery Neolithic migrations into Anatolia

We present the first ancient DNA data from the Pre-Pottery Neolithic of Mesopotamia (Southeastern Turkey and Northern Iraq), Cyprus, and the Northwestern Zagros, along with the first data from Neolithic Armenia. We show that these and neighboring populations were formed through admixture of pre-Neolithic sources related to Anatolian, Caucasus, and Levantine hunter-gatherers, forming a Neolithic continuum of ancestry mirroring the geography of West Asia. By analyzing Pre-Pottery and Pottery Neolithic populations of Anatolia, we show that the former were derived from admixture between Mesopotamian-related and local Epipaleolithic-related sources, but the latter experienced additional Levantine-related gene flow, thus documenting at least two pulses of migration from the Fertile Crescent heartland to the early farmers of Anatolia

A genetic probe into the ancient and medieval history of Southern Europe and West Asia

Literary and archaeological sources have preserved a rich history of Southern Europe and West Asia since the Bronze Age that can be complemented by genetics. Mycenaean period elites in Greece did not differ from the general population and included both people with some steppe ancestry and others, like the Griffin Warrior, without it. Similarly, people in the central area of the Urartian Kingdom around Lake Van lacked the steppe ancestry characteristic of the kingdom’s northern provinces. Anatolia exhibited extraordinary continuity down to the Roman and Byzantine periods, with its people serving as the demographic core of much of the Roman Empire, including the city of Rome itself. During medieval times, migrations associated with Slavic and Turkic speakers profoundly affected the region